4th Annual Conference on Stem Cell and Regenerative Medicine

  Stem cells are self-renewing cells that can be differentiated into other cell types. Conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2D) cultures. The design of three-dimensional (3D) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissue formation. Biodegradable scaffolds play an important role in creating a 3D environment to induce tissue formation. The application of scaffolding materials together with stem cell technologies are believed to hold enormous potential for tissue regeneration. In this review, we provide an overview of application of tissue engineered scaffolds and stem cells for the development of stem cell-based engineered tissue replacements. In particular, we focus on bone marrow stem cells (BMSCs) and mesenchymal stem cell (MSCs) due to their extensive clinical applications. Stem cells are primitive c...

  There is a solid connection between slightness, aggravation, and the hindered capacity to fix tissue injury because of diminishes in endogenous undifferentiated cell creation. In spite of the fact that activity and dietary supplementation give advantage to fragile patients, there are presently no particular treatments for slightness. Definition and Epidemiology of Frailty Fragility has been clinically characterized as "a condition of expanded weakness coming about because of maturing related decrease for possible later use and capacity across various organ frameworks to such an extent that the capacity to adapt to consistently or intense stressors is compromised". Integral to this geriatric clinical disorder is the idea that it has various causes and givers that lead to the trademark diminishes in strength, perseverance, movement, energy levels, and physiologic capacity, which increment the powerlessness to reliance and passing. Of note, despite the fact that delicacy i...